SCHEMBL434372

SCHEMBL434372

C=C(C)C(=O)NCCc1ncc[nH]1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.49
TBXAS1 P24557 2/20 0.45
NAMPT P43490 6/20 0.42
FDPS P14324 1/20 0.40
FPR2 P25090 1/20 0.39
HTT P42858 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
MTNR1A P48039 1/20 0.36
HTR1A P08908 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
QPCT Q16769 1/20 0.36
QPCTL Q9NXS2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935332 0.91 TBXAS1 (0.50) TERTTBXAS1NAMPT
Hydrochloric Acid SCHEMBL8108651 0.90 TBXAS1 (0.51) TERTTBXAS1NAMPT
SCHEMBL9081976 0.85 TERT (0.53) TERTTBXAS1NAMPTFDPSFPR2
SCHEMBL7426540 0.80 TERT (0.54) TERTTBXAS1NAMPTFDPSFPR2
SCHEMBL17470979 0.79 SMN1; SMN2 (0.52) TERTTBXAS1NAMPTFPR2MTNR1A
SCHEMBL1142559 0.79 TBXAS1 (0.43) TERTTBXAS1NAMPTFDPSFPR2
SCHEMBL13034815 0.78 TERT (0.49) TERTTBXAS1NAMPTFPR2HRH4
SCHEMBL16768654 0.78 TERT (0.49) TERTTBXAS1NAMPTFDPSFPR2
SCHEMBL16133628 0.78 TERT (0.49) TERTTBXAS1NAMPTFDPSFPR2
SCHEMBL7198930 0.78 TERT (0.49) TERTTBXAS1NAMPTFDPSFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US claimed
EP-0707077-B1 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same ORTHO CLINICAL DIAGNOSTICS INC (US) 2004-11-17 EP claimed
EP-0702006-B1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLIN DIAG (US) 2000-05-10 EP claimed
US-5582988-A PRECIPITAION OF NUCLEIC ACID AND CATION POLYMER AT ACIDIC PH; ADJUSTMENT OF PH TO RELEASE NUCLEIC ACID JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-12-10 US claimed
US-5523368-A Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-06-04 US claimed
EP-0707077-A2 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-17 EP claimed
EP-0702006-A1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-20 EP claimed
US-12630582-B2 Method for biomaterial purification and kits thereof Life Technologies Corporation (US) 2026-05-19 US disclosed
US-20250367610-A1 Block Copolymers Grafted to Porous Polymeric Substrate SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-04 US disclosed
EP-4543575-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE Solventum Intellectual Properties Company (US) 2025-04-30 EP disclosed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
US-20240059731-A1 Method for Biomaterial Purification and Kits Thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-02-22 US disclosed
US-20240010674-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-01-11 US disclosed
WO-2000066783-A2 RAPID AND EFFICIENT CAPTURE OF DNA FROM SAMPLE WITHOUT USING CELL LYSING REAGENT ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2000-11-09 WO disclosed
EP-0702006-B1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLIN DIAG (US) 2000-05-10 EP disclosed
US-5582988-A PRECIPITAION OF NUCLEIC ACID AND CATION POLYMER AT ACIDIC PH; ADJUSTMENT OF PH TO RELEASE NUCLEIC ACID JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-12-10 US disclosed
US-5523368-A Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-06-04 US disclosed
EP-0707077-A2 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-17 EP disclosed
EP-0702006-A1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-20 EP disclosed
US-5434270-A Weakly basic polymerizable monomers and polymers prepared therefrom EASTMAN KODAK COMPANY (US) 1995-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059731-A1 Method for Biomaterial Purification and Kits Thereof BMP2, ADM2, PLOD3 TERT 1545/4885TBXAS1 2459/4885NAMPT 3388/4885
US-12630582-B2 Method for biomaterial purification and kits thereof CD68, FIBP, BMP2 TERT 834/4885TBXAS1 3108/4885NAMPT 3608/4885
US-20240010674-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION CD68, PLAUR, BMP2 TERT 3493/4885TBXAS1 4346/4885NAMPT 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.