Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 4/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428225 | 1.00 | ACHE (0.34) | ACHEOPRM1OPRD1OPRK1SLC7A5 | |
| SCHEMBL7426885 | 0.93 | ACHE (0.35) | ACHEOPRM1OPRD1OPRK1SLC7A5 | |
| SCHEMBL7428803 | 0.92 | ACHE (0.34) | ACHEOPRM1OPRD1OPRK1SLC7A5 | |
| Trifluoroacetic Acid SCHEMBL5213057 | 0.91 | ACHE (0.34) | ACHEOPRK1SLC7A5NAMPT | |
| Trifluoroacetic Acid SCHEMBL5212873 | 0.91 | ACHE (0.34) | ACHEOPRK1SLC7A5NAMPT | |
| SCHEMBL7431168 | 0.88 | ACHE (0.38) | ACHEOPRM1OPRD1OPRK1CFD | |
| Trifluoroacetic Acid SCHEMBL7422801 | 0.86 | ACHE (0.35) | ACHEOPRM1OPRD1OPRK1CFD | |
| Trifluoroacetic Acid SCHEMBL7424902 | 0.85 | ACHE (0.34) | ACHESLC7A5NAMPT | |
| Trifluoroacetic Acid SCHEMBL7431702 | 0.83 | NAMPT (0.34) | ACHEOPRK1SLC7A5NAMPT | |
| Trifluoroacetic Acid SCHEMBL7428691 | 0.82 | CFD (0.43) | ACHECFDNPC1RAB9ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240154-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| EP-1192135-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001044226-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |