Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 2/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.30 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7428691 | 0.90 | CFD (0.43) | ACHECFDHTR2CNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL7423644 | 0.90 | ACHE (0.39) | ACHEOPRM1OPRD1OPRK1ADRA2C | |
| Trifluoroacetic Acid SCHEMBL5212837 | 0.87 | ACHE (0.36) | ACHECFDHTR2CADRA2C | |
| Trifluoroacetic Acid SCHEMBL5213057 | 0.87 | ACHE (0.34) | ACHEOPRK1HTR2C | |
| Trifluoroacetic Acid SCHEMBL5212873 | 0.87 | ACHE (0.34) | ACHEOPRK1HTR2C | |
| SCHEMBL7431168 | 0.87 | ACHE (0.38) | ACHEOPRM1OPRD1OPRK1CFD | |
| SCHEMBL7427153 | 0.86 | ACHE (0.34) | ACHEOPRM1OPRD1OPRK1CFD | |
| SCHEMBL7428225 | 0.86 | ACHE (0.34) | ACHEOPRM1OPRD1OPRK1CFD | |
| Trifluoroacetic Acid SCHEMBL7424902 | 0.85 | ACHE (0.34) | ACHE | |
| Trifluoroacetic Acid SCHEMBL5210906 | 0.85 | ACHE (0.39) | ACHEOPRM1OPRD1SLC6A4ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192135-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |