Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7423644 | 0.90 | ACHE (0.39) | ACHEKDM1A | |
| Trifluoroacetic Acid SCHEMBL7422801 | 0.90 | ACHE (0.35) | CFDHTR2CNPC1RAB9AACHE | |
| Trifluoroacetic Acid SCHEMBL5210906 | 0.86 | ACHE (0.39) | ACHEHDAC8HDAC6KDM1AKLKB1 | |
| Trifluoroacetic Acid SCHEMBL6486974 | 0.85 | ACHE (0.38) | KDM4EACHEMAPTKLKB1 | |
| Trifluoroacetic Acid SCHEMBL5212837 | 0.85 | ACHE (0.36) | CFDHTR2CACHEHDAC8HDAC6 | |
| SCHEMBL7431168 | 0.84 | ACHE (0.38) | CFDNPC1RAB9AACHEHASPIN | |
| Trifluoroacetic Acid SCHEMBL5213057 | 0.83 | ACHE (0.34) | HTR2CACHEHDAC8HDAC6NAMPT | |
| Trifluoroacetic Acid SCHEMBL5212873 | 0.83 | ACHE (0.34) | HTR2CACHEHDAC8HDAC6NAMPT | |
| Trifluoroacetic Acid SCHEMBL7431702 | 0.82 | NAMPT (0.34) | HTR2CACHEHDAC8HDAC6NAMPT | |
| SCHEMBL7428225 | 0.82 | ACHE (0.34) | CFDNPC1RAB9AACHENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240154-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001044226-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |