Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424237 | 0.87 | MEN1 (0.44) | ALDH1A1FNTAFNTBPGGT1BKMT2A | |
| SCHEMBL7427703 | 0.79 | FOLH1 (0.52) | ALDH1A1FOLH1KMT2AMEN1 | |
| SCHEMBL7427744 | 0.78 | PPARA (0.48) | ALDH1A1FNTAFNTBPGGT1BANPEP | |
| SCHEMBL7426722 | 0.78 | ALDH1A1 (0.54) | ALDH1A1FNTAFNTBPGGT1BFOLH1 | |
| SCHEMBL391430 | 0.78 | FOLH1 (0.60) | ALDH1A1ANPEPENPEPFOLH1NPC1 | |
| SCHEMBL7434454 | 0.77 | FOLH1 (0.59) | ALDH1A1ANPEPENPEPFOLH1NPC1 | |
| SCHEMBL7435223 | 0.74 | FOLH1 (0.52) | ALDH1A1ANPEPENPEPFOLH1 | |
| SCHEMBL7433519 | 0.74 | NPC1 (0.53) | ALDH1A1FOLH1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7431248 | 0.74 | FOLH1 (0.49) | ALDH1A1ANPEPENPEPFOLH1SMN1; SMN2 | |
| SCHEMBL7435388 | 0.73 | NPC1 (0.52) | ALDH1A1FOLH1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |