Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432902 | 0.87 | ALDH1A1 (0.46) | PPARAALDH1A1MMEACEGAA | |
| SCHEMBL7432011 | 0.86 | ALDH1A1 (0.45) | PPARAALDH1A1MMEACEGAA | |
| SCHEMBL7427744 | 0.84 | PPARA (0.48) | PPARAALDH1A1PTGDRNPC1RAB9A | |
| SCHEMBL392082 | 0.82 | ALDH1A1 (0.52) | PPARAALDH1A1MMEACESMN1; SMN2 | |
| SCHEMBL7431904 | 0.79 | NR1H4 (0.48) | PPARAALDH1A1MMEACESMN1; SMN2 | |
| SCHEMBL7436878 | 0.79 | MME (0.55) | ALDH1A1MMEACESMN1; SMN2KMT2A | |
| SCHEMBL7431217 | 0.78 | KCNK3 (0.46) | PPARAALDH1A1MMEACEGAA | |
| SCHEMBL7431596 | 0.77 | NPC1 (0.49) | PPARAALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL7432008 | 0.77 | KMT2A (0.43) | PPARAALDH1A1MMEACEGAA | |
| SCHEMBL7429797 | 0.76 | PPARA (0.48) | PPARAALDH1A1GAASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |