Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.60 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84572 | 0.83 | GSK3B (0.60) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| SCHEMBL10948430 | 0.83 | PLOD2 (0.83) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| Bromide SCHEMBL6118414 | 0.81 | GSK3B (0.58) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| Bromide SCHEMBL66813 | 0.81 | GSK3B (0.58) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL899290 | 0.81 | GSK3B (0.58) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| Bromide SCHEMBL2773952 | 0.79 | GSK3B (0.56) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| SCHEMBL1038505 | 0.79 | PTPN1 (0.68) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| SCHEMBL200805 | 0.77 | PLOD2 (0.73) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 | |
| SCHEMBL11599481 | 0.76 | GSK3B (0.70) | ALDH1A1HPGDKDM4ELMNAGAA | |
| SCHEMBL27908337 | 0.76 | ALDH1A1 (0.55) | PLOD2CYP3A4PLOD3PLOD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329070-A1 | Cardiotonic alkanoyl and aroyl oxazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-23 | — | — | EP | disclosed |