Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.60 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.57 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.57 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL899290 | 0.98 | GSK3B (0.58) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| Bromide SCHEMBL66813 | 0.98 | GSK3B (0.58) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| Bromide SCHEMBL6118414 | 0.98 | GSK3B (0.58) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| Bromide SCHEMBL2773952 | 0.96 | GSK3B (0.56) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| Bromide SCHEMBL9203773 | 0.86 | GSK3B (0.63) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| Pyridine SCHEMBL18321129 | 0.83 | GSK3B (0.76) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| SCHEMBL7428121 | 0.83 | PLOD2 (0.60) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| SCHEMBL7265428 | 0.82 | PLOD2 (0.53) | GSK3BPTPN1PLOD2PLOD3PLOD1 | |
| SCHEMBL205280 | 0.82 | GSK3B (0.80) | GSK3BPTPN1 | |
| SCHEMBL10948430 | 0.80 | PLOD2 (0.83) | PLOD2PLOD3PLOD1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388582-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | ILDONG PHARMACEUTICAL CO LTD (KR) | 2025-12-25 | — | — | US | disclosed |
| EP-4556476-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2025-05-21 | — | — | EP | disclosed |
| EP-4139286-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |
| US-20250011315-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | PRISM MEDICINES, INC. | 2025-01-09 | — | — | US | disclosed |
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| EP-3962915-B1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2024-09-04 | — | — | EP | disclosed |
| US-12036210-B2 | Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia | ATROGI AB (SE) | 2024-07-16 | — | — | US | disclosed |
| US-12036210-B2 | Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia | ATROGI AB (SE) | 2024-07-16 | — | — | US | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| EP-0321490-A4 | INHIBITION OF INTERLEUKIN-1 PRODUCTION BY MONOCYTES AND/OR MACROPHAGES. | SMITHKLINE BECKMAN CORP (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0321490-A1 | INHIBITION OF INTERLEUKIN-1 PRODUCTION BY MONOCYTES AND/OR MACROPHAGES. | SMITHKLINE BECKMAN CORP (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4751310-A | Inhibition of the 5-lipoxygenase pathway | SMITHKLINE BECKMAN CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| WO-1988001169-A1 | INHIBITION OF INTERLEUKIN-1 PRODUCTION BY MONOCYTES AND/OR MACROPHAGES | SMITHKLINE BECKMAN CORPORATION (US) | 1988-02-25 | — | — | WO | disclosed |
| US-4725606-A | AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4719218-A | ENZYME INHIBITORS | SMITHKLINE BECKMAN CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4697012-A | IMMUNOLOGY, ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0231622-A2 | Inhibition of the 5-lipoxygenase pathway | SMITHKLINE BEECHAM CORPORATION (US) | 1987-08-12 | — | — | EP | disclosed |
| EP-0169502-A2 | 2-Benzyl-4-(2-morpholino)-4-Pyriol) Thiazole | MERCK & CO. INC. (US) | 1986-01-29 | — | — | EP | disclosed |
| EP-0165810-A2 | Benzofuran and benzothiophene derivatives, their use in inhibiting mammalian leukotriene biosynthesis, and pharmaceutical compositions containing these derivatives | MERCK FROSST CANADA INC. (CA) | 1985-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011315-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | AHR, ARNT, HCAR1 | GSK3B 3183/4885PTPN1 1910/4885PLOD2 1446/4885 |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | AHR, ARNT, HCAR1 | GSK3B 3183/4885PTPN1 1910/4885PLOD2 1446/4885 |
| US-20250388582-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | GBA1, PIKFYVE, MAN2B1 | GSK3B 3174/4885PTPN1 862/4885PLOD2 4232/4885 |
| US-12036210-B2 | Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia | SLC5A2, SLC5A1, GPR119 | GSK3B 949/4885PTPN1 4090/4885PLOD2 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.