Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443888 | 0.93 | POLB (0.48) | POLBALDH1A1HTTKDM4ERAB9A | |
| SCHEMBL7439415 | 0.92 | POLB (0.49) | POLBALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL7447128 | 0.92 | RAB9A (0.52) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7435917 | 0.91 | POLB (0.48) | POLBALDH1A1L3MBTL1HTTRAB9A | |
| SCHEMBL7434360 | 0.91 | POLB (0.59) | POLBKMT2AALDH1A1L3MBTL1HTT | |
| SCHEMBL7434317 | 0.89 | POLB (0.46) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7430181 | 0.89 | POLB (0.48) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7446327 | 0.89 | SMN1; SMN2 (0.52) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7439756 | 0.88 | POLB (0.45) | POLBALDH1A1L3MBTL1RAB9ALMNA | |
| SCHEMBL7432822 | 0.88 | CA1 (0.49) | POLBALDH1A1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |