Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443888 | 0.93 | POLB (0.48) | POLBLMNANPSR1RAB9AALDH1A1 | |
| SCHEMBL7495736 | 0.92 | TSHR (0.49) | POLBATMLMNANPSR1TSHR | |
| SCHEMBL7439415 | 0.92 | POLB (0.49) | POLBATMLMNANPSR1AIMP2 | |
| SCHEMBL7447128 | 0.92 | RAB9A (0.52) | POLBLMNANPSR1RAB9AALDH1A1 | |
| SCHEMBL7428136 | 0.91 | POLB (0.48) | POLBLMNANPSR1TSHRRAB9A | |
| SCHEMBL7434360 | 0.91 | POLB (0.59) | POLBATMLMNATSHRRAB9A | |
| SCHEMBL7447951 | 0.91 | DRD4 (0.50) | POLBLMNANPSR1TSHRAIMP2 | |
| SCHEMBL7434317 | 0.89 | POLB (0.46) | POLBATMLMNANPSR1AIMP2 | |
| SCHEMBL7446327 | 0.89 | SMN1; SMN2 (0.52) | POLBTSHRRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL7430181 | 0.89 | POLB (0.48) | POLBLMNANPSR1TSHRAIMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |