Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443888 | 0.94 | POLB (0.48) | RAB9ALMNAPOLBHTTNPC1 | |
| SCHEMBL7439415 | 0.93 | POLB (0.49) | RAB9ALMNAPOLBGAAHTT | |
| SCHEMBL7428136 | 0.92 | POLB (0.48) | RAB9ALMNAPOLBGAAHTT | |
| SCHEMBL7435917 | 0.92 | POLB (0.48) | RAB9ALMNAPOLBHTTL3MBTL1 | |
| SCHEMBL7434360 | 0.92 | POLB (0.59) | RAB9ALMNAPOLBGAAHTT | |
| SCHEMBL7446327 | 0.91 | SMN1; SMN2 (0.52) | RAB9APOLBGAAHTTL3MBTL1 | |
| SCHEMBL7433767 | 0.91 | DRD4 (0.53) | RAB9ANPC1ALDH1A1 | |
| SCHEMBL7434317 | 0.91 | POLB (0.46) | RAB9ALMNAPOLBGAAHTT | |
| SCHEMBL7436573 | 0.91 | HTT (0.47) | RAB9ALMNAPOLBGAAHTT | |
| SCHEMBL7439756 | 0.91 | POLB (0.45) | RAB9ALMNAPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |