Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443888 | 0.93 | POLB (0.48) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL7429340 | 0.92 | POLB (0.49) | POLBDRD4ALDH1A1TSHRKMT2A | |
| SCHEMBL7447128 | 0.92 | RAB9A (0.52) | POLBALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7439415 | 0.92 | POLB (0.49) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL7435917 | 0.91 | POLB (0.48) | POLBDRD4ALDH1A1TSHRLMNA | |
| SCHEMBL7428136 | 0.91 | POLB (0.48) | POLBALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7430181 | 0.91 | POLB (0.48) | POLBDRD4ALDH1A1TSHRKMT2A | |
| SCHEMBL7434317 | 0.89 | POLB (0.46) | POLBDRD4ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7446327 | 0.89 | SMN1; SMN2 (0.52) | POLBALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7432822 | 0.88 | CA1 (0.49) | POLBALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |