Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441765 | 0.85 | TSHR (0.52) | RAB9AKMT2ATSHRALDH1A1PPIA | |
| Hydrochloric Acid SCHEMBL7433994 | 0.84 | RAB9A (0.53) | RAB9ALMNAKMT2ATDP1TSHR | |
| Hydrochloric Acid SCHEMBL7430581 | 0.84 | RAB9A (0.59) | RAB9AKMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL7434607 | 0.80 | ALDH1A1 (0.52) | RAB9AKMT2ATSHRALDH1A1PPIA | |
| SCHEMBL7430642 | 0.79 | ALDH1A1 (0.54) | RAB9ALMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL5077520 | 0.79 | RAB9A (0.53) | RAB9AKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7428258 | 0.77 | RAB9A (0.53) | RAB9ALMNAKMT2ATDP1TSHR | |
| SCHEMBL7438960 | 0.77 | RAB9A (0.47) | RAB9AKMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL7428252 | 0.77 | RAB9A (0.52) | RAB9ALMNAKMT2ATDP1TSHR | |
| SCHEMBL7435433 | 0.76 | NPSR1 (0.52) | RAB9AKMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |