Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.45 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.45 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434975 | 0.90 | RAB9A (0.63) | RAB9ALMNAKMT2ATDP1ECE1 | |
| Hydrochloric Acid SCHEMBL7433987 | 0.86 | RAB9A (0.52) | RAB9ALMNAKMT2ATDP1GPR132 | |
| SCHEMBL7431259 | 0.85 | FOLH1 (0.52) | RAB9AECE1ALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL7430564 | 0.84 | RAB9A (0.56) | RAB9AROCK2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7432001 | 0.84 | FOLH1 (0.51) | RAB9AECE1ALDH1A1MAPTHTT | |
| SCHEMBL7440850 | 0.83 | MAPT (0.60) | RAB9AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7429686 | 0.83 | RAB9A (0.55) | RAB9ALMNAKMT2ATDP1ROCK2 | |
| SCHEMBL7433322 | 0.81 | ALDH1A1 (0.58) | RAB9ALMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7428258 | 0.81 | RAB9A (0.53) | RAB9ALMNAKMT2ATDP1GPR132 | |
| SCHEMBL9724784 | 0.81 | PKM (0.62) | RAB9AKMT2AECE1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |