Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434607 | 0.82 | ALDH1A1 (0.52) | ALDH1A1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL7435433 | 0.82 | NPSR1 (0.52) | ALDH1A1RAB9AMAPTSMN1; SMN2HIF1A | |
| SCHEMBL5077520 | 0.81 | RAB9A (0.53) | ALDH1A1RAB9ASMN1; SMN2HIF1AMEN1 | |
| Hydrochloric Acid SCHEMBL7438259 | 0.81 | RAB9A (0.47) | ALDH1A1RAB9AMAPTSMN1; SMN2HIF1A | |
| Hydrochloric Acid SCHEMBL7430581 | 0.81 | RAB9A (0.59) | ALDH1A1RAB9AMAPTHPGDTDP1 | |
| SCHEMBL7438960 | 0.79 | RAB9A (0.47) | ALDH1A1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL7428263 | 0.79 | RAB9A (0.54) | ALDH1A1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL7430630 | 0.77 | RAB9A (0.48) | ALDH1A1RAB9AMAPTSMN1; SMN2HIF1A | |
| SCHEMBL7431261 | 0.75 | KCNK3 (0.49) | ALDH1A1RAB9AMAPTSMN1; SMN2HIF1A | |
| SCHEMBL20280575 | 0.75 | PHLPP2 (0.54) | ALDH1A1RAB9AMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |