SCHEMBL2493371

SCHEMBL2493371

FC(F)(Br)C(F)(F)ONc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.35
TDP1 Q9NUW8 3/20 0.35
HSD17B10 Q99714 2/20 0.35
CTSD P07339 1/20 0.35
MAPT P10636 5/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
AR P10275 1/20 0.34
TSHR P16473 3/20 0.33
PTGS2 P35354 2/20 0.33
ALOX15 P16050 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALOX12 P18054 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
MAPK1 P28482 1/20 0.33
HTR2B P41595 1/20 0.33
IDO1 P14902 2/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586608 0.81 ALDH1A1 (0.33) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL742856 0.79 ALDH1A1 (0.39) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL15391808 0.76 ALDH1A1 (0.36) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL9225004 0.72 ALDH1A1 (0.37) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL633340 0.72 CFTR (0.34) ALDH1A1TDP1HSD17B10CTSDMAPT
Toluene SCHEMBL27973589 0.71 TSHR (0.44) ALDH1A1TDP1CTSDMAPTMEN1
SCHEMBL50027 0.70 TSHR (0.42) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL31114495 0.69 PDK1 (0.36) ALDH1A1TDP1HSD17B10CTSDMAPT
SCHEMBL28285341 0.69 PDK1 (0.43) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL10583635 0.69 LMNA (0.38) ALDH1A1TDP1HSD17B10CTSDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011213642-A TRIFLUOROVINYLOXY-N-MONOALKYLANILINE COMPOUND AND METHOD FOR PRODUCING THE SAME UNIMATEC CO LTD 2011-10-27 JP disclosed