Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.38 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.38 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.38 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.38 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022009 | 0.89 | LMNA (0.41) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL7431043 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL7485729 | 0.85 | LMNA (0.39) | ALDH1A1MAPK1RECQLLMNAMAPT | |
| SCHEMBL11207157 | 0.85 | KMT2A (0.45) | ALDH1A1L3MBTL1LMNAMAPTPOLB | |
| SCHEMBL7432809 | 0.85 | LMNA (0.41) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL11207422 | 0.84 | KCNA3 (0.42) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL7429435 | 0.84 | TDP1 (0.49) | ALDH1A1L3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL11017511 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL11203299 | 0.83 | KCNA3 (0.41) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL11201202 | 0.83 | KCNA3 (0.41) | ALDH1A1LMNAMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |