Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480796 | 0.81 | ALDH1A1 (0.45) | KMT2AMAPTNPSR1MEN1SMN1; SMN2 | |
| SCHEMBL7480793 | 0.81 | ALDH1A1 (0.45) | KMT2AMAPTNPSR1MEN1SMN1; SMN2 | |
| SCHEMBL2387532 | 0.80 | GLS (0.46) | PKMKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL25815905 | 0.77 | MAPT (0.33) | PKMCASP6TSHRKMT2AMAPT | |
| SCHEMBL30337762 | 0.77 | MAPT (0.33) | PKMCASP6TSHRKMT2AMAPT | |
| SCHEMBL25816150 | 0.77 | MAPT (0.33) | PKMCASP6TSHRKMT2AMAPT | |
| SCHEMBL7818824 | 0.75 | KMT2A (0.43) | PKMCASP6KMT2AMAPTHTT | |
| SCHEMBL7818827 | 0.75 | KMT2A (0.43) | PKMCASP6KMT2AMAPTHTT | |
| SCHEMBL7739985 | 0.75 | POLB (0.38) | PKMTSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL6649819 | 0.74 | MEN1 (0.36) | PKMCASP6TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |