Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480793 | 1.00 | ALDH1A1 (0.45) | ALDH1A1EDNRAEDNRBCYP1A2CYP2C19 | |
| SCHEMBL7428719 | 0.81 | PKM (0.39) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL916737 | 0.77 | ALDH1A1 (0.53) | ALDH1A1EDNRAEDNRBMEN1KMT2A | |
| SCHEMBL28850201 | 0.77 | ALDH1A1 (0.53) | ALDH1A1EDNRAEDNRBMEN1KMT2A | |
| SCHEMBL11013839 | 0.74 | FGFR1 (0.42) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8886472 | 0.74 | FGFR1 (0.42) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8886471 | 0.74 | FGFR1 (0.42) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL25248267 | 0.73 | NOTUM (0.40) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL782668 | 0.73 | NOTUM (0.40) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL782667 | 0.73 | NOTUM (0.40) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |