SCHEMBL25816150

SCHEMBL25816150

COC(=O)C1C/C(=N/O)c2cccc(Br)c21

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
MAPK10 P53779 1/20 0.33
KMT2A Q03164 1/20 0.33
PTK2B Q14289 1/20 0.33
NCOA1 Q15788 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
PKM P14618 1/20 0.33
CASP6 P55212 1/20 0.33
PDE5A O76074 2/20 0.32
KIF11 P52732 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ITGA4 P13612 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30337762 1.00 MAPT (0.33) MAPTMEN1TSHRHTTMAPK10
SCHEMBL25815905 1.00 MAPT (0.33) MAPTMEN1TSHRHTTMAPK10
SCHEMBL30338328 0.82 KIF11 (0.36) MAPTMEN1KMT2APDE5AKIF11
SCHEMBL25816149 0.82 KIF11 (0.36) MAPTMEN1KMT2APDE5AKIF11
SCHEMBL7428719 0.77 PKM (0.39) MAPTMEN1TSHRHTTMAPK10
SCHEMBL30967887 0.70 ACHE (0.41) MAPTMEN1KMT2APDE5AKIF11
SCHEMBL4018743 0.70 ACHE (0.41) MAPTMEN1KMT2APDE5AKIF11
SCHEMBL7818827 0.68 KMT2A (0.43) MAPTHTTKMT2ASMN1; SMN2PKM
SCHEMBL7818824 0.68 KMT2A (0.43) MAPTHTTKMT2ASMN1; SMN2PKM
SCHEMBL28908862 0.68 ALDH1A1 (0.46) MAPTMEN1TSHRHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867346-B Kinase inhibitors GB005股份有限公司 2025-03-14 CN disclosed
US-20230219923-A1 KINASE INHIBITORS VIDYA THERAPEUTICS, INC. 2023-07-13 US disclosed
US-20230219923-A1 KINASE INHIBITORS VIDYA THERAPEUTICS, INC. 2023-07-13 US disclosed
CN-115867346-A Kinase inhibitors GB005股份有限公司 2023-03-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219923-A1 KINASE INHIBITORS BTK, ABL1, LYN MAPT 2417/4885MEN1 3526/4885TSHR 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.