Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylglycyl SCHEMBL7423505 | 0.84 | ACE (0.46) | TAAR1ACEEPHX1EPHX2NPC1 | |
| SCHEMBL6423726 | 0.83 | GGT1 (0.57) | ACESMN1; SMN2GGT1 | |
| SCHEMBL7758672 | 0.81 | GGT1 (0.50) | ACESMN1; SMN2GGT1 | |
| SCHEMBL7384292 | 0.81 | MMP3 (0.46) | ACEEPHX2GGT1 | |
| SCHEMBL7385252 | 0.80 | ACE (0.44) | ACEEPHX2GGT1 | |
| SCHEMBL7427350 | 0.79 | GGT1 (0.48) | ACENPC1RAB9ASMN1; SMN2GGT1 | |
| Alanine SCHEMBL7382718 | 0.76 | GGT1 (0.50) | ACETSHRSMN1; SMN2GGT1 | |
| Homophenylalanine SCHEMBL7383933 | 0.76 | GGT1 (0.50) | ACESMN1; SMN2GGT1 | |
| SCHEMBL7763119 | 0.76 | OPRK1 (0.52) | ACEGGT1 | |
| Glutamic Acid SCHEMBL7375280 | 0.75 | GGT1 (0.49) | ACEGGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047450-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032150-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |