Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428726 | 0.90 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL7434150 | 0.88 | LIPG (0.40) | GABRA1GABRB2 | |
| SCHEMBL7434000 | 0.87 | LIPG (0.42) | — | |
| SCHEMBL310156 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2 | |
| SCHEMBL7426926 | 0.83 | SIGMAR1 (0.38) | — | |
| SCHEMBL381275 | 0.83 | DAO (0.31) | — | |
| SCHEMBL6339207 | 0.81 | MGLL (0.34) | GABRA1GABRB2 | |
| SCHEMBL815763 | 0.78 | LIPG (0.34) | — | |
| SCHEMBL2661090 | 0.77 | KCNH2 (0.38) | — | |
| SCHEMBL816546 | 0.76 | LIPG (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212306-A2 | HYDROXYALKANOYLAMINOLACTAMS AND RELATED STRUCTURES AS INHIBITORS OF ABETA PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1137649-A2 | PROCESS FOR THE PREPARATION OF PYRIMIDINONE DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-04 | — | — | EP | disclosed |
| WO-2001019797-A2 | HYDROXYALKANOYL AMINOLACTAMS AND RELATED STRUCTURES AS INHIBITORS OF Aβ PROTEIN PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-03-22 | — | — | WO | disclosed |
| WO-2000034286-A2 | PROCESS FOR THE PREPARATION OF PYRIMIDINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-15 | — | — | WO | disclosed |