SCHEMBL74290

SCHEMBL74290

CC(C)(C)c1ccc(-c2c(-c3ccc(C(C)(C)C)cc3C(C)(C)C)c(-c3ccc(C(C)(C)C)cc3C(C)(C)C)c3c(c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)=c2ccccc2=3)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 1/20 0.43
PLA2G1B P04054 1/20 0.43
NFKB1 P19838 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
NR1I2 O75469 1/20 0.35
KIF11 P52732 2/20 0.34
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463259 0.95 ALDH1A1 (0.40) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL253424 0.94 ALDH1A1 (0.39) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Phosphoric Acid SCHEMBL7250820 0.91 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Hypophosphorous Acid SCHEMBL1286596 0.91 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL16440136 0.91 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Phosphoric Acid SCHEMBL9195605 0.91 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL672499 0.86 ALDH1A1 (0.43) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1903606 0.86 NPC1 (0.38) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL228138 0.85 ALDH1A1 (0.53) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1902890 0.84 ALDH1A1 (0.39) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6157 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117265218-A Quenching oil special for precision gear, preparation and use method 马鞍山金泉工业介质科技有限公司 2023-12-22 CN claimed
CN-117265217-A Large-size high-carbon high-chromium alloy casting ball quenching oil, preparation and use methods thereof 马鞍山金泉工业介质科技有限公司 2023-12-22 CN claimed
CN-114585676-B Polyethylene composition for use with recycled polyethylene SABIC环球技术有限责任公司 2023-09-29 CN claimed
WO-2023114134-A1 HEAT-STABILIZED, FLAME RETARDANT POLYMER COMPOSITION CELANESE INTERNATIONAL CORPORATION (US) 2023-06-22 WO claimed
US-11591467-B2 Thermoplastic polymer composites and methods for preparing, collecting, and tempering 3D printable materials and articles from same G6 MATERIALS CORP. (US) 2023-02-28 US claimed
US-11572455-B2 Antidegradant blend SI GROUP, INC. (US) 2023-02-07 US claimed
CN-110869429-B Polyethylene composition SABIC环球技术有限责任公司 2023-02-07 CN claimed
CN-115286588-A Process for preparing pentamethylene isocyanurate 中海油常州涂料化工研究院有限公司 2022-11-04 CN claimed
CN-115260706-A Polymer foam particles, method for the production and use thereof, and products or moldings 朗盛性能材料有限责任公司 2022-11-01 CN claimed
CN-114685857-A Efficient composite additive and LLDPE (linear low density polyethylene) composition for blown film 山东省临沂市三丰化工有限公司 2022-07-01 CN claimed
US-4670489-A PHOTOSTABILIZERS FOR PAINTS, RESINS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1987-06-02 US claimed
EP-0212496-A1 Hindered hydroxyphenylalkanoates of ethoxylated bisphenol a and stabilized compositions ICI AMERICAS INC. (US) 1987-03-04 EP claimed
EP-0211663-A2 Thermally resistant polyolefin composition Sumitomo Chemical Industries Ltd. (JP) 1987-02-25 EP claimed
US-4645853-A Hindered phenolic oxamide compounds and stabilized compositions ICI AMERICAS INC. (US) 1987-02-24 US claimed
EP-0197951-A4 FILM LAMINATE FOR STERILE FLEXIBLE CONTAINERS. FUJIMORI KOGYO CO LTD (JP) 1987-02-03 EP claimed
EP-0197951-A1 FILM LAMINATE FOR STERILE FLEXIBLE CONTAINERS. FUJIMORI KOGYO CO LTD (JP) 1986-10-22 EP claimed
US-4613638-A OXIDATION AND HEAT RESISTANCE FOR SYNTHETIC POLYMERS ICI AMERICAS INC. (US) 1986-09-23 US claimed
US-4598113-A Hindered hydroxyphenylalkanoates of ethoxylated bisphenol A and stabilized compositions ICI AMERICAS INC. (US) 1986-07-01 US claimed
US-4593057-A Polymers from ethylenically unsaturated monomers ICI AMERICAS INC. (US) 1986-06-03 US claimed
WO-1986002041-A1 FILM LAMINATE FOR STERILE FLEXIBLE CONTAINERS FUJIMORI KOGYO CO., LTD. (JP) 1986-04-10 WO claimed