Hypophosphorous Acid

Hypophosphorous Acid

SCHEMBL1286596

CC(C)(C)c1ccc(-c2c(-c3ccc(C(C)(C)C)cc3C(C)(C)C)c(-c3ccc(C(C)(C)C)cc3C(C)(C)C)c3c(c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)=c2ccccc2=3)c(C(C)(C)C)c1.O=[PH2]O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
PLA2G1B P04054 1/20 0.41
NFKB1 P19838 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
NR1I2 O75469 1/20 0.33
ACLY P53396 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
APEX1 P27695 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74290 0.91 ALDH1A1 (0.43) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL463259 0.90 ALDH1A1 (0.40) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Phosphoric Acid SCHEMBL9195605 0.89 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Phosphoric Acid SCHEMBL7250820 0.89 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL16440136 0.89 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL253424 0.88 ALDH1A1 (0.39) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL672499 0.79 ALDH1A1 (0.43) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1903606 0.78 NPC1 (0.38) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL228138 0.78 ALDH1A1 (0.53) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Hypophosphorous Acid SCHEMBL30634526 0.77 RXRA (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4303267-A1 THERMOPLASTIC POLYESTER ELASTOMER COMPOSITION, PREPARATION METHOD THEREFOR AND MOLDED ARTICLE COMPRISING SAME LG CHEM, LTD. (KR) 2024-01-10 EP disclosed
US-10428189-B2 Process and composition for well dispersed, highly loaded color masterbatch CHROMA COLOR CORPORATION (US) 2019-10-01 US disclosed
US-20180258237-A1 PROCESS AND COMPOSITION FOR WELL DISPERSED, HIGHLY LOADED COLOR MASTERBATCH CHROMA COLOR CORPORATION 2018-09-13 US disclosed
US-9969881-B2 Process and composition for well-dispersed, highly loaded color masterbatch CAROLINA COLOR CORPORATION (US) 2018-05-15 US disclosed
EP-3169535-A1 PROCESS AND COMPOSITION FOR WELL-DISPERSED, HIGHLY LOADED COLOR MASTERBATCH Carolina Color Corporation (US) 2017-05-24 EP disclosed
EP-2236560-B1 POLYARYLENE SULFIDE RESIN COMPOSITION, PRODUCTION METHOD THEREOF AND SURFACE MOUNT ELECTRONIC COMPONENT DAINIPPON INK & CHEMICALS (JP) 2017-03-01 EP disclosed
US-20160017144-A1 PROCESS AND COMPOSITION FOR WELL DISPERSED, HIGHLY LOADED COLOR MASTERBATCH CHROMA COLOR CORPORATION 2016-01-21 US disclosed
WO-2016010815-A1 PROCESS AND COMPOSITION FOR WELL-DISPERSED, HIGHLY LOADED COLOR MASTERBATCH CAROLINA COLOR CORPORATION (US) 2016-01-21 WO disclosed
US-9040611-B2 Highly loaded concentrate pellets and preparation of the same E-Z COLOR CORPORATION (US) 2015-05-26 US disclosed
US-20140245927-A1 HIGHLY LOADED CONCENTRATE PELLETS AND PREPARATION OF THE SAME E-Z COLOR CORPORATION 2014-09-04 US disclosed
WO-2008104531-A1 METHOD TO MANUFACTURE A COMPARTMENTALIZED PELLET DIRECTLY FROM A REACTOR M & G POLIMERI ITALIA S.P.A. (IT) 2008-09-04 WO disclosed
US-20080207843-A1 Method To Manufacture A Compartmentalized Pellet Directly From A Reactor M&G USA CORPORATION 2008-08-28 US disclosed
US-6986945-B2 Process for manufacturing multilayer pellets and use of the multilayer pellets SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-17 US disclosed
EP-1273596-B1 FLEXIBLE POLYPROPYLENE RESIN IDEMITSU KOSAN CO (JP) 2005-03-30 EP disclosed
US-6855756-B2 Soft polypropylene resin having a melt index falling in a specific range, prepared by melting and kneading a propylene homo or copolymer each having specific properties in presence of a radical generating agent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2005-02-15 US disclosed
US-6669986-B1 Extrusion of quick-drying molding materials comprising thermoplastic resins having core and sheath structures used as plastics SUMIKA COLOR COMPANY, LIMITED (JP) 2003-12-30 US disclosed
US-20030055137-A1 Soft polypropylene resin having a melt index falling in a specific range, prepared by melting and kneading a propylene homo or copolymer each having specific properties in presence of a radical generating agent PRIME POLYMER CO., LTD. (JP) 2003-03-20 US disclosed
EP-1273596-A1 FLEXIBLE POLYPROPYLENE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-08 EP disclosed
EP-1063070-A2 Process for manufacturing multilayer pellets and use of the multilayer pellets Sumika Color Company Limited (JP) 2000-12-27 EP disclosed
US-5807914-A POLYCARBONATE OLIGOMER, POLYSILOXANE-POLYACRYLATE COMPOSITE RUBBER GRAFTED WITH ACRYLONITRILE AND STYRENE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1998-09-15 US disclosed