Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9195605 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| SCHEMBL74290 | 0.91 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| SCHEMBL463259 | 0.90 | ALDH1A1 (0.40) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| SCHEMBL16440136 | 0.89 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| Hypophosphorous Acid SCHEMBL1286596 | 0.89 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| SCHEMBL253424 | 0.88 | ALDH1A1 (0.39) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| Phosphoric Acid SCHEMBL28490434 | 0.83 | NPC1 (0.42) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| Phosphoric Acid SCHEMBL18138471 | 0.80 | PGK1 (0.38) | PTPN5MEN1GAAKMT2ANPSR1 | |
| Phosphoric Acid SCHEMBL8431601 | 0.80 | PTPN5 (0.41) | ALDH1A1RAB9ANPC1CASP3SENP8 | |
| Phosphoric Acid SCHEMBL8431599 | 0.80 | PTPN5 (0.41) | ALDH1A1RAB9ANPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075262-B | Composite materials with enhanced electrical conductivity and methods of making the same | LG化学株式会社 | 2020-05-12 | — | — | CN | disclosed |
| US-6629769-B2 | Article comprising molded polyester resin composition article with light-reflecting metal layer having, after being molded, specified average surface roughness and deflection temperature under load | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2003-10-07 | — | — | US | disclosed |
| US-20020075686-A1 | Polyester resin composition and light-reflecting molded article thereof | TOYO BOSEKI KABUSIKI KAISYA (JP) | 2002-06-20 | — | — | US | disclosed |