Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 13/20 | 0.57 |
| ▸ | IL1B | P01584 | 4/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443313 | 0.91 | CASP1 (0.59) | CASP1IL1BCAPN1CTSB | |
| SCHEMBL7277133 | 0.83 | CASP1 (0.56) | CASP1IL1BCAPN1 | |
| SCHEMBL7431065 | 0.80 | CASP1 (0.63) | CASP1IL1BCTSB | |
| SCHEMBL21254145 | 0.77 | SLC6A9 (0.56) | SLC6A9SLC6A5F2 | |
| SCHEMBL7284663 | 0.75 | CASP1 (0.51) | CASP1IL1B | |
| SCHEMBL15444282 | 0.75 | CASP1 (0.52) | CASP1IL1BCAPN1CTSB | |
| SCHEMBL29359869 | 0.74 | OPRD1 (0.57) | CTSB | |
| SCHEMBL6157629 | 0.72 | CASP1 (1.00) | CASP1 | |
| SCHEMBL6157640 | 0.72 | CASP1 (1.00) | CASP1 | |
| SCHEMBL29434553 | 0.72 | CTSS (0.54) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519748-A2 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | claimed |