Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426506 | 0.92 | MMP2 (0.45) | MMP2LPAR1LPAR5ACHEFNTA | |
| SCHEMBL7423137 | 0.87 | FFAR1 (0.48) | MMP2LPAR1LPAR5ACHENPY5R | |
| SCHEMBL7428192 | 0.86 | CARM1 (0.46) | LPAR1LPAR5ACHEALDH1A1PPARA | |
| SCHEMBL22654344 | 0.81 | MCHR1 (0.37) | NR3C1 | |
| SCHEMBL7425601 | 0.81 | MCHR1 (0.50) | MMP2FNTAPGGT1B | |
| SCHEMBL7426467 | 0.79 | GRIA2 (0.43) | — | |
| SCHEMBL7427033 | 0.79 | GRIA2 (0.43) | — | |
| SCHEMBL7421295 | 0.78 | PPARG (0.41) | PPARAEPHX2 | |
| SCHEMBL7417897 | 0.78 | FOLH1 (0.45) | — | |
| SCHEMBL7427123 | 0.78 | LTB4R (0.44) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |