Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423137 | 0.87 | FFAR1 (0.48) | LPAR1LPAR5ACHEFFAR1NPY5R | |
| SCHEMBL7424617 | 0.87 | MAOB (0.42) | FFAR1 | |
| SCHEMBL7429166 | 0.86 | MMP2 (0.39) | LPAR1LPAR5PPARAACHEALDH1A1 | |
| SCHEMBL7419020 | 0.85 | GRN (0.38) | ALDH1A1GRNSORT1 | |
| SCHEMBL7419478 | 0.85 | MMP2 (0.42) | PPARGPPARAALDH1A1GRNSORT1 | |
| SCHEMBL7426506 | 0.85 | MMP2 (0.45) | LPAR1LPAR5PPARAACHE | |
| SCHEMBL7422445 | 0.83 | SLC1A5 (0.40) | LPAR1LPAR5PPARAGRNSORT1 | |
| SCHEMBL7426638 | 0.79 | ALDH1A1 (0.43) | PPARGPPARAALDH1A1GRNSORT1 | |
| SCHEMBL7417897 | 0.78 | FOLH1 (0.45) | — | |
| SCHEMBL7424530 | 0.78 | LTB4R (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |