Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426506 | 0.89 | MMP2 (0.45) | MCHR1AOC3TAAR1MMP2FNTA | |
| SCHEMBL7424796 | 0.88 | HPGD (0.38) | MCHR1MMP3S1PR1MEN1KMT2A | |
| SCHEMBL7420384 | 0.87 | MMP12 (0.46) | MCHR1GPR88CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7427409 | 0.87 | MMP12 (0.46) | MCHR1GPR88CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7418362 | 0.86 | PSEN1 (0.51) | MMP3MMP2 | |
| SCHEMBL7419478 | 0.84 | MMP2 (0.42) | MCHR1MMP3S1PR1MMP2MME | |
| SCHEMBL7424015 | 0.84 | GPR88 (0.42) | MCHR1MMP2GPR88MME | |
| SCHEMBL7417897 | 0.83 | FOLH1 (0.45) | MEN1KMT2AMMEACE | |
| SCHEMBL7378945 | 0.83 | MEN1 (0.48) | MMP3AOC3TAAR1MMP2MEN1 | |
| SCHEMBL7429166 | 0.81 | MMP2 (0.39) | MMP2FNTAPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |