Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418650 | 0.94 | PGK1 (0.44) | TDP1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL27667787 | 0.89 | ALDH1A1 (0.52) | TDP1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL80615 | 0.84 | TNKS2 (0.47) | ALDH1A1KDM4ECA2PGK1PGK2 | |
| SCHEMBL8417016 | 0.84 | PTGS1 (0.37) | TDP1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL1247063 | 0.84 | PGK1 (0.38) | TDP1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL13180741 | 0.84 | CNR1 (0.38) | TDP1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL16962202 | 0.84 | TACR1 (0.38) | TDP1ALDH1A1KDM4EALOX5GAA | |
| SCHEMBL28266224 | 0.82 | TNKS2 (0.41) | ALDH1A1KDM4ECA2PGK1PGK2 | |
| SCHEMBL3690305 | 0.82 | ALDH1A1 (0.44) | ALDH1A1PGK1PGK2TSHRIDH1 | |
| SCHEMBL11766486 | 0.80 | CALM1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102154431-A | Kinetic resolution method of secondary alcohol | UNIV ZHEJIANG | 2011-08-17 | — | — | CN | claimed |
| CN-102127584-A | Dynamic kinetic method for resolving secondary alcohol | UNIV ZHEJIANG | 2011-07-20 | — | — | CN | claimed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| CN-113493450-B | Ligand compound, preparation method thereof and application thereof in asymmetric reaction | 中国科学院福建物质结构研究所 | 2023-07-25 | — | — | CN | disclosed |
| EP-3915998-B1 | APPLICATION OF SALIDROSIDE DERIVATIVE IN SKIN-WHITENING AGENT FOR EXTERNAL USE | SHANGHAI CHEERMORE BIOLOGICAL TECH CO LTD (CN) | 2023-01-18 | — | — | EP | disclosed |
| CN-113493450-A | Ligand compound, preparation method thereof and application thereof in asymmetric reaction | 中国科学院福建物质结构研究所 | 2021-10-12 | — | — | CN | disclosed |
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |
| CN-108503579-A | Fentanyl analog and its application | 南京医科大学 | 2018-09-07 | — | — | CN | disclosed |
| CN-102154431-A | Kinetic resolution method of secondary alcohol | UNIV ZHEJIANG | 2011-08-17 | — | — | CN | disclosed |
| CN-102127584-A | Dynamic kinetic method for resolving secondary alcohol | UNIV ZHEJIANG | 2011-07-20 | — | — | CN | disclosed |
| CN-100376292-C | Deodorant composition | TAKASAGO PERFUMERY CO LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| CN-1732019-A | Deodorant composition | TAKASAGO PERFUMERY CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1263755-A2 | CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | Bristol-Myers Squibb Pharma Company (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001070673-A2 | CYCLIC β-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-$g(a) | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-0191394-B1 | ISOTHIOUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT UNDESIRABLE PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1989-12-06 | — | — | EP | disclosed |
| US-4689068-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1987-08-25 | — | — | US | disclosed |
| EP-0191394-A1 | Isothioureas, process for their preparation and their use to combat undesirable plant growth | BASF Aktiengesellschaft (DE) | 1986-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | TDP1 1025/4885ALDH1A1 4776/4885KDM4E 710/4885 |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | TDP1 1025/4885ALDH1A1 4776/4885KDM4E 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.