Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430657 | 0.89 | ALDH1A1 (0.47) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL7427603 | 0.83 | NPSR1 (0.48) | KMT2AMEN1ALDH1A1MAPTUSP2 | |
| SCHEMBL7433262 | 0.82 | RAB9A (0.43) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL7429896 | 0.81 | ALDH1A1 (0.57) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL7441506 | 0.81 | CASR (0.49) | KMT2AMEN1NPC1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7433991 | 0.79 | RAB9A (0.51) | KMT2AMEN1ALDH1A1CYP3A4RAB9A | |
| SCHEMBL7429429 | 0.77 | KMT2A (0.50) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL7441468 | 0.76 | ALDH1A1 (0.53) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL20097869 | 0.73 | RAB9A (0.58) | KMT2AMEN1POLBNPC1ALDH1A1 | |
| SCHEMBL7436997 | 0.73 | CREBBP (0.45) | KMT2AMEN1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |