Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429896 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7430657 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7425606 | 0.74 | MEN1 (0.54) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL7430576 | 0.74 | CYP1A2 (0.49) | CREBBPALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7429436 | 0.73 | KMT2A (0.51) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL7431939 | 0.72 | HTT (0.49) | ALDH1A1TSHRGAAKDM4EMAPT | |
| SCHEMBL7433262 | 0.72 | RAB9A (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11936746 | 0.71 | CREBBP (0.52) | CREBBPALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7433991 | 0.71 | RAB9A (0.51) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL7441506 | 0.71 | CASR (0.49) | ALDH1A1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |