Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429436 | 0.89 | KMT2A (0.51) | ALDH1A1RAB9AUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL7427603 | 0.85 | NPSR1 (0.48) | ALDH1A1USP2HSD17B10MAPTCASR | |
| SCHEMBL7433262 | 0.85 | RAB9A (0.43) | ALDH1A1RAB9AUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL7429896 | 0.84 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL7441506 | 0.83 | CASR (0.49) | ALDH1A1RAB9AUSP2HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7433991 | 0.81 | RAB9A (0.51) | ALDH1A1RAB9AMAPTHTTKMT2A | |
| SCHEMBL7441468 | 0.76 | ALDH1A1 (0.53) | ALDH1A1RAB9AHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL7430654 | 0.75 | RAB9A (0.50) | ALDH1A1RAB9AUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL7436997 | 0.75 | CREBBP (0.45) | ALDH1A1HSD17B10MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7430566 | 0.75 | ALDH1A1 (0.45) | ALDH1A1RAB9AUSP2HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |