Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018732 | 0.99 | RAB9A (0.37) | MMERAB9ATSHRFKBP1AKMT2A | |
| SCHEMBL11290034 | 0.91 | TSHR (0.37) | MMETSHRKMT2ALMNAMEN1 | |
| SCHEMBL7486243 | 0.89 | ABCB11 (0.42) | MMESPHK1FKBP1AKMT2ALMNA | |
| SCHEMBL11018542 | 0.83 | KDM4E (0.38) | KMT2ALMNAMEN1KDM4ECACNA1C | |
| SCHEMBL11299822 | 0.83 | ABCB11 (0.42) | MMERAB9ASPHK1LMNAFFAR4 | |
| SCHEMBL11297976 | 0.81 | MAPT (0.41) | MMERAB9ATSHRLMNAFFAR4 | |
| SCHEMBL11016516 | 0.80 | NPSR1 (0.35) | RAB9ATSHRKMT2ALMNAKDM4E | |
| SCHEMBL11210936 | 0.80 | NAAA (0.40) | — | |
| SCHEMBL11201942 | 0.79 | THRA (0.36) | FKBP1AKMT2ALMNAMEN1KDM4E | |
| SCHEMBL11206652 | 0.79 | THRA (0.36) | FKBP1AKMT2ALMNAMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |