Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 14/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.62 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504004 | 0.91 | HTR4 (0.81) | HTR4ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8718481 | 0.89 | HTR4 (0.71) | HTR4ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8718478 | 0.89 | HTR4 (0.71) | HTR4ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7428799 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL7439648 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL7428794 | 0.88 | ALDH1A1 (0.83) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL7439485 | 0.84 | HTR3A (0.68) | HTR4ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7430281 | 0.84 | HTR3A (0.68) | HTR4ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7338420 | 0.83 | HTR3A (0.70) | HTR4ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7343233 | 0.83 | HTR3A (0.70) | HTR4ALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469449-B1 | Diazabicyclononyl derivatives as 5-HT3 receptor antagonists | NISSHIN FLOUR MILLING CO (JP) | 1997-10-01 | — | — | EP | disclosed |
| US-5256656-A | Antiserotonine agent | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5187166-A | Also useful as antipsychotic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0469449-A1 | Azabicyclo derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |