Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192279 | 0.95 | ADRA1A (0.42) | MAOBMEN1KMT2AALOX5L3MBTL1 | |
| SCHEMBL8290989 | 0.87 | TAAR1 (0.40) | MAOBL3MBTL1MAOAMAPTHTR2A | |
| SCHEMBL4839006 | 0.84 | MAOB (0.46) | MAOBMAOASIGMAR1MAPTRXFP1 | |
| SCHEMBL8638637 | 0.82 | L3MBTL1 (0.44) | MAOBMEN1KMT2AALOX5L3MBTL1 | |
| SCHEMBL19974058 | 0.78 | SIGMAR1 (0.41) | MEN1KMT2AALOX5SIGMAR1 | |
| SCHEMBL7307286 | 0.77 | ADRA1A (0.42) | MEN1KMT2AL3MBTL1MAOASIGMAR1 | |
| SCHEMBL563886 | 0.76 | TP53 (0.41) | MAOBHTR2A | |
| SCHEMBL13992719 | 0.73 | CNR2 (0.40) | MAOBL3MBTL1 | |
| SCHEMBL6014668 | 0.73 | MEN1 (0.50) | MEN1KMT2AMAOASIGMAR1MAPT | |
| SCHEMBL2357339 | 0.72 | MAPT (0.52) | MAOBALOX5MAOASIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |