Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812669 | 0.85 | MAOB (0.53) | MAOBSMN1; SMN2 | |
| SCHEMBL11488455 | 0.84 | LMNA (0.39) | TP53LOXL2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10051635 | 0.83 | TAAR1 (0.40) | TP53IDO1ALDH1A1SMN1; SMN2CYP2A6 | |
| SCHEMBL27579738 | 0.82 | LOXL2 (0.43) | PPIDLOXL2ALDH1A1TSHRMAOB | |
| SCHEMBL5482816 | 0.82 | IDO1 (0.41) | TP53IDO1ALDH1A1SMN1; SMN2CYP2A6 | |
| SCHEMBL11488537 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL969878 | 0.81 | TSHR (0.46) | LOXL2IDO1ALDH1A1TSHRMAOB | |
| SCHEMBL8814962 | 0.80 | ESR1 (0.40) | TP53IDO1ALDH1A1TAAR1 | |
| SCHEMBL8290989 | 0.80 | TAAR1 (0.40) | TP53LOXL2ALDH1A1MAOBCMA1 | |
| SCHEMBL27557933 | 0.80 | TAAR1 (0.38) | IDO1SMN1; SMN2HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185132-B1 | NOVEL ETHYL BENZYLPHOSPHINATE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND THEIR USE AS CALCIUM ANTAGONIST | KANEBO, LTD. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-4607031-A | REACTING A PHOSPHONOCHLORIDATE HYDROCHLORIDE WITH ALKALI METAL SALT OF LACTAM | KANEBO LTD. (JP) | 1986-08-19 | — | — | US | claimed |
| EP-0185132-A1 | Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist | KANEBO, LTD. (JP) | 1986-06-25 | — | — | EP | claimed |
| EP-2957514-B1 | MULTI-LAYER BOTTLE AND METHOD FOR PRODUCING SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-10144548-B2 | Multi-layer bottle and method for producing same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2018-12-04 | — | — | US | disclosed |
| US-20160001914-A1 | MULTI-LAYER BOTTLE AND METHOD FOR PRODUCING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-01-07 | — | — | US | disclosed |
| EP-2957514-A1 | MULTI-LAYER BOTTLE AND METHOD FOR PRODUCING SAME | Mitsubishi Gas Chemical Company, Inc. (JP) | 2015-12-23 | — | — | EP | disclosed |
| EP-1673377-B1 | PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXYPROPYLPHOSPHINIC ACID DERIVATIVES | AVENTIS PHARMA INC (US) | 2013-12-25 | — | — | EP | disclosed |
| EP-2038290-B1 | MODULATORS OF TOLL-LIKE RECEPTOR 7 | GILEAD SCIENCES INC (US) | 2013-09-04 | — | — | EP | disclosed |
| US-8338593-B2 | Agonists; Treatment of Hepatitis C virus; phosphinate-substituted purine derivatives | GILEAD SCIENCES, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120034480-A1 | Catalyst for producing polyesters and polyester resin composition | SAKAMOTO JUN (JP) | 2012-02-09 | — | — | US | disclosed |
| US-5407922-A | GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| US-5229379-A | Gamma-aminobutyric acid antagonists | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0185132-B1 | NOVEL ETHYL BENZYLPHOSPHINATE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND THEIR USE AS CALCIUM ANTAGONIST | KANEBO, LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |
| US-4607031-A | REACTING A PHOSPHONOCHLORIDATE HYDROCHLORIDE WITH ALKALI METAL SALT OF LACTAM | KANEBO LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
| US-4607031-A | REACTING A PHOSPHONOCHLORIDATE HYDROCHLORIDE WITH ALKALI METAL SALT OF LACTAM | KANEBO LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
| US-4607031-A | REACTING A PHOSPHONOCHLORIDATE HYDROCHLORIDE WITH ALKALI METAL SALT OF LACTAM | KANEBO LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
| EP-0185132-A1 | Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist | KANEBO, LTD. (JP) | 1986-06-25 | — | — | EP | disclosed |
| EP-0185132-A1 | Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist | KANEBO, LTD. (JP) | 1986-06-25 | — | — | EP | disclosed |
| EP-0185132-A1 | Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist | KANEBO, LTD. (JP) | 1986-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034480-A1 | Catalyst for producing polyesters and polyester resin composition | PUF60, RPS24, SRP54 | TP53 1839/4885PPID 3477/4885LOXL2 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.