Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 3/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426149 | 0.84 | MMP1 (0.42) | NTSR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5869411 | 0.80 | MMP1 (0.39) | NTSR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5869421 | 0.80 | MMP1 (0.39) | NTSR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5869408 | 0.80 | MMP1 (0.39) | NTSR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7424540 | 0.80 | MAPK1 (0.42) | NTSR1 | |
| SCHEMBL7429670 | 0.71 | ACKR3 (0.35) | NPSR1 | |
| SCHEMBL7374947 | 0.67 | ACE2 (0.39) | NTSR1NPSR1 | |
| SCHEMBL7426808 | 0.66 | MMP1 (0.46) | NTSR1MMP1MMP9MMP3 | |
| SCHEMBL5870191 | 0.65 | MMP1 (0.48) | NTSR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5869703 | 0.65 | MMP1 (0.48) | NTSR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |