Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426149 | 0.89 | MMP1 (0.42) | NTSR1FOLH1 | |
| SCHEMBL5869290 | 0.82 | MAPK1 (0.44) | MAPK1NTSR1OPRK1FOLH1ACE2 | |
| SCHEMBL5869287 | 0.82 | MAPK1 (0.44) | MAPK1NTSR1OPRK1FOLH1ACE2 | |
| SCHEMBL5869299 | 0.82 | MAPK1 (0.44) | MAPK1NTSR1OPRK1FOLH1ACE2 | |
| SCHEMBL7429682 | 0.80 | NTSR1 (0.37) | NTSR1 | |
| SCHEMBL7424533 | 0.73 | AOC3 (0.39) | MAPK1SLC2A1ALDH1A1TAAR1 | |
| SCHEMBL5869641 | 0.71 | ACE2 (0.48) | MAPK1NTSR1ACE2ACEGRN | |
| SCHEMBL5869646 | 0.71 | ACE2 (0.48) | MAPK1NTSR1ACE2ACEGRN | |
| SCHEMBL5869636 | 0.71 | ACE2 (0.48) | MAPK1NTSR1ACE2ACEGRN | |
| SCHEMBL5870188 | 0.70 | MMP1 (0.48) | NTSR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |