Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210978 | 0.89 | SERPINE1 (0.45) | SYKMAPK1IDO1ADRB2ADRB1 | |
| SCHEMBL8457758 | 0.85 | IDO1 (0.62) | SYKMAPK1HIF1AIDO1TDP1 | |
| SCHEMBL6290022 | 0.81 | TDP1 (0.50) | SYKIDO1TDP1ADRB2ADRB1 | |
| SCHEMBL28216226 | 0.81 | ADRB2 (0.50) | SYKIDO1TDP1ADRB2ADRB1 | |
| SCHEMBL28868029 | 0.80 | IDO1 (0.54) | SYKIDO1TDP1ADRB2SLC6A3 | |
| SCHEMBL20590258 | 0.80 | TDP1 (0.58) | IDO1TDP1LMNAKMT2AMEN1 | |
| SCHEMBL28547245 | 0.79 | LMNA (0.49) | MAPK1HIF1ATDP1ADRB2ADRB1 | |
| SCHEMBL20107564 | 0.79 | SERPINE1 (0.47) | IDO1TDP1ADRB2ADRB1ADRB3 | |
| SCHEMBL27830259 | 0.79 | TDP1 (0.59) | SYKMAPK1HIF1ATDP1ADRB2 | |
| SCHEMBL16648476 | 0.78 | ADRB2 (0.56) | SYKMAPK1HIF1ATDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302414-A | Oxazole, oxadiazole and indole derivatives useful for inhibiting USP28 | 卡莫特医疗有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112574255-B | Organic arsine-based CDK inhibitor and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2024-05-10 | — | — | CN | disclosed |
| US-11613547-B2 | G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment | UNIVERSITY OF HEALTH SCIENCES & PHARMACY IN ST. LOUIS (US) | 2023-03-28 | — | — | US | disclosed |
| CN-113646329-A | Glucose-sensitive insulin derivatives | 诺和诺德股份有限公司 | 2021-11-12 | — | — | CN | disclosed |
| US-20210061814-A1 | G-PROTEIN BIASED OPIOID RECEPTOR AGONIST/ANALGESICS WITH REDUCED ARRESTIN RECRUITMENT | ST. LOUIS COLLEGE OF PHARMACY (US) | 2021-03-04 | — | — | US | disclosed |
| CN-105101970-A | Beta-lactamase inhibitors | VENATORX PHARMACEUTICALS INC | 2015-11-25 | — | — | CN | disclosed |
| CN-1950343-B | Amine-based basic compound and use thereof | KUREHA CORP | 2013-06-19 | — | — | CN | disclosed |
| CN-1950343-A | Amine-based basic compound and use thereof | KUREHA CORP (JP) | 2007-04-18 | — | — | CN | disclosed |
| CN-1309719-C | Derivative of phenylamide pyrimidine and application thereof | CHEN GUOQING (CN) | 2007-04-11 | — | — | CN | disclosed |
| CN-1560050-A | Derivative of phenylamide pyrimidine and application thereof | 陈国庆 | 2005-01-05 | — | — | CN | disclosed |
| EP-1073624-A1 | AMINOMETHYL-BENZOIC ESTER DERIVATIVES AS TRYPTASE INHIBITORS | Proteus Molecular Design Limited (GB) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055661-A1 | AMINOMETHYL-BENZOIC ESTER DERIVATIVES AS TRYPTASE INHIBITORS | PROTEUS MOLECULAR DESIGN LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061814-A1 | G-PROTEIN BIASED OPIOID RECEPTOR AGONIST/ANALGESICS WITH REDUCED ARRESTIN RECRUITMENT | OPRK1, OPRL1, ARRB1 | SYK 3977/4885MAPK1 1509/4885HIF1A 1659/4885 |
| US-11613547-B2 | G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment | OPRK1, OPRL1, ARRB1 | SYK 3977/4885MAPK1 1509/4885HIF1A 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.