Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571996 | 0.78 | HIF1A (0.44) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL8251 | 0.76 | NOS2 (0.43) | CYP2A6MIFTRPA1GRIN1GRIN2B | |
| SCHEMBL7867205 | 0.74 | ALDH1A1 (0.44) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL921157 | 0.73 | HIF1A (0.52) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL721250 | 0.72 | HIF1A (0.56) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL6335562 | 0.72 | HIF1A (0.56) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL8837171 | 0.70 | HIF1A (0.48) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL1885696 | 0.70 | MIF (0.54) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL8837167 | 0.70 | HIF1A (0.48) | HIF1ACYP2A6MIFTRPA1CYP2E1 | |
| SCHEMBL15999404 | 0.69 | HIF1A (0.52) | HIF1ACYP2A6MIFTRPA1CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000012492-A1 | BENZOXAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |