Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351941 | 0.78 | HKDC1 (0.35) | MEN1ALDH1A1PRNPMAPTHPGD | |
| SCHEMBL7434824 | 0.76 | ALOX15 (0.33) | ALDH1A1HTT | |
| SCHEMBL1699606 | 0.74 | DYRK1A (0.35) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5143271 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL1451102 | 0.72 | ESR2 (0.39) | ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL27717336 | 0.70 | POLB (0.34) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11212949 | 0.67 | KDM4E (0.44) | MEN1ALDH1A1PRNPMAPTHPGD | |
| SCHEMBL6152174 | 0.65 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL629844 | 0.65 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL17351003 | 0.65 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283310-B1 | N-BENZHYDRYL-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-5028610-A | Calcium Channel Blockers | SANKYO COMPANY LIMITED (JP) | 1991-07-02 | — | — | US | disclosed |