Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761358 | 0.78 | HDAC6 (0.39) | ALDH1A1RAB9APAX8TSHRCHRNB2 | |
| Fluorobenzene SCHEMBL27926129 | 0.78 | KCNN4 (0.46) | KMT2AALDH1A1PKMMEN1RAB9A | |
| SCHEMBL25255853 | 0.74 | HDAC6 (0.35) | RAB9ACHRNB2CHRNA4 | |
| SCHEMBL7200107 | 0.74 | RAB9A (0.57) | KMT2AALDH1A1MEN1RAB9AL3MBTL1 | |
| SCHEMBL21132832 | 0.74 | ALDH1A1 (0.50) | KMT2AALDH1A1PKMMEN1RAB9A | |
| SCHEMBL12096699 | 0.74 | HDAC6 (0.37) | ALDH1A1RAB9ATSHRCHRNB2CHRNA4 | |
| Fluorobenzene SCHEMBL28079208 | 0.74 | THRB (0.39) | KMT2AALDH1A1MEN1RAB9ATSHR | |
| SCHEMBL1507907 | 0.73 | KCNN4 (0.41) | MAOAMAOBKMT2AALDH1A1MEN1 | |
| SCHEMBL27536175 | 0.73 | MEN1 (0.41) | KMT2AALDH1A1MEN1RAB9AL3MBTL1 | |
| SCHEMBL30568129 | 0.72 | PAX8 (0.41) | KMT2AALDH1A1MEN1RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609625-A1 | Inhibitors of HIV protease useful for the treatment of AIDS | ELI LILLY AND COMPANY (US) | 1994-08-10 | — | — | EP | disclosed |