Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431647 | 0.84 | CA2 (0.49) | PTGS1PTGS2CA2IDO1KMT2A | |
| Hydrochloric Acid SCHEMBL7426281 | 0.79 | CA2 (0.50) | PTGS1PTGS2CA2IDO1RAB9A | |
| SCHEMBL19743651 | 0.76 | MTNR1A (0.51) | KMT2AMEN1PKMMTNR1AMTNR1B | |
| SCHEMBL22778023 | 0.75 | ALDH1A1 (0.52) | KMT2AMEN1PKMMTNR1AMTNR1B | |
| SCHEMBL27595683 | 0.74 | PTGS1 (0.59) | PTGS1PTGS2CA2IDO1SLC22A12 | |
| SCHEMBL649744 | 0.72 | PTGS1 (0.70) | PTGS1PTGS2CA2PKMSLC22A12 | |
| SCHEMBL7024493 | 0.71 | MEN1 (0.49) | KMT2AMEN1PKMMTNR1AMTNR1B | |
| SCHEMBL25433158 | 0.70 | KDM4E (0.62) | KMT2AMEN1PKMMTNR1AMTNR1B | |
| SCHEMBL7072684 | 0.70 | MTNR1A (0.77) | KMT2AMTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL7425113 | 0.70 | MEN1 (0.51) | KMT2AMEN1PKMMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117651-A1 | NEW BIS-BENZIMIDAZOLES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020401-A1 | NEW BIS-BENZIMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |