Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 9/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595683 | 0.90 | PTGS1 (0.59) | PTGS1PTGS2PTPN1CA2SLC22A12 | |
| SCHEMBL10417318 | 0.84 | PTGS1 (0.59) | PTGS1PTGS2TSHRPTPN1CA2 | |
| SCHEMBL4372207 | 0.83 | PTGS1 (1.00) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL10416897 | 0.83 | PTGS1 (0.58) | PTGS1PTGS2PTPN1SLC22A12 | |
| SCHEMBL11187994 | 0.79 | PTGS1 (0.56) | PTGS1PTGS2TSHRPTPN1CA2 | |
| SCHEMBL8719438 | 0.78 | PTGS2 (0.68) | PTGS1PTGS2TSHRACLYL3MBTL1 | |
| SCHEMBL9232555 | 0.78 | TSHR (0.54) | PTGS1PTGS2TSHRCA2ACLY | |
| SCHEMBL6001500 | 0.77 | PTPN1 (0.86) | PTGS1PTGS2PTPN1CA2 | |
| SCHEMBL27182622 | 0.77 | TSHR (0.53) | PTGS1PTGS2TSHRCA2ACLY | |
| SCHEMBL6000980 | 0.76 | PTPN1 (0.63) | PTGS1PTGS2PTPN1CA2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| CN-117986154-A | Antiparasitic compounds | 英特维特国际股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20240043385-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE | INTERVET INC. (US) | 2024-02-08 | — | — | US | disclosed |
| US-20240043446-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | INTERVET INC. (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4284509-A1 | ANTIPARASITIC COMPOUNDS | Intervet International B.V. (NL) | 2023-12-06 | — | — | EP | disclosed |
| CN-116964031-A | Antiparasitic compounds | 英特维特国际股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116600807-A | Insect repellent compound comprising thienopyridine structure | 英特维特国际股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-20230148316-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE | INTERVET INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230110397-A1 | ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE | INTERVET INC. (US) | 2023-04-13 | — | — | US | disclosed |
| EP-2545777-B2 | Use of an isoxazoline composition as antiparasitic | INTERVET INT BV (NL) | 2023-01-18 | — | — | EP | disclosed |
| WO-2007079010-A2 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING-PLOUGH LTD. (CH) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155799-A1 | CARBONATES OF FENICOL ANTIBIOTICS | INTERVET INC. | 2007-07-05 | — | — | US | disclosed |
| EP-1799636-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | Schering-Plough Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006135648-A2 | CONTROL OF PARASITES IN ANIMALS BY N-[(PHENYLOXY)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE AND N-[(PHENYLSULFANYL)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
| US-20060128779-A1 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-06-15 | — | — | US | disclosed |
| WO-2006055565-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF PARASITICIDAL 2-PHENYL-3-(1H-PYRROL-2-YL) ACRYLONITRILE DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006034333-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-03-30 | — | — | WO | disclosed |
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH LTD. (CH) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043385-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE | HRH4, PNPO, NME4 | PTGS1 450/4885PTGS2 533/4885TSHR 4610/4885 |
| US-20060128779-A1 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | PNN, AADAC, EPX | PTGS1 460/4885PTGS2 185/4885TSHR 3265/4885 |
| US-20070155799-A1 | CARBONATES OF FENICOL ANTIBIOTICS | CYP4F3, TET1, CYP4F2 | PTGS1 589/4885PTGS2 1206/4885TSHR 3125/4885 |
| US-20240043446-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | DHODH, NISCH, DDT | PTGS1 177/4885PTGS2 187/4885TSHR 2866/4885 |
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | TRHDE, DDT, EPHX1 | PTGS1 1332/4885PTGS2 1406/4885TSHR 1334/4885 |
| US-20230148316-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE | DHX35, DDX5, DHODH | PTGS1 806/4885PTGS2 698/4885TSHR 4731/4885 |
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | ELANE, CTRL, PIGO | PTGS1 296/4885PTGS2 1435/4885TSHR 2010/4885 |
| US-20230110397-A1 | ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE | AADAC, HNMT, NISCH | PTGS1 1492/4885PTGS2 1123/4885TSHR 4483/4885 |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | PRDX5, TUBA3C, TUBA1C | PTGS1 1988/4885PTGS2 1369/4885TSHR 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.