Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422714 | 0.96 | MEN1 (0.43) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL7432301 | 0.87 | LMNA (0.53) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL6264573 | 0.87 | LMNA (0.53) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL7426444 | 0.87 | MAPT (0.52) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL6263163 | 0.87 | MAPT (0.52) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL6259595 | 0.86 | ABCB11 (0.50) | MAPK1ABCB11LMNAMAPTKMT2A | |
| SCHEMBL6265451 | 0.85 | L3MBTL1 (0.46) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL7438468 | 0.85 | MAPT (0.50) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL11205507 | 0.84 | NAAA (0.42) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11300087 | 0.83 | MAPK1 (0.65) | MAPK1ABCB11LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |