Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GCK | P35557 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442335 | 0.92 | ALDH1A1 (0.52) | PKMALDH1A1POLBNPY2RKDM4E | |
| SCHEMBL10460811 | 0.90 | ALDH1A1 (0.52) | PKMALDH1A1POLBNPY2RKDM4E | |
| SCHEMBL10460341 | 0.87 | NPY2R (0.55) | PKMALDH1A1NPY2RKDM4EL3MBTL1 | |
| SCHEMBL10461596 | 0.86 | MEN1 (0.56) | PKMALDH1A1POLBNPY2RKMT2A | |
| SCHEMBL10460610 | 0.86 | NPY2R (0.49) | PKMALDH1A1POLBNPY2RKDM4E | |
| SCHEMBL7432420 | 0.85 | ALDH1A1 (0.55) | PKMALDH1A1POLBKDM4EHPGD | |
| SCHEMBL5915273 | 0.82 | NPY2R (0.60) | PKMALDH1A1NPY2RKDM4EL3MBTL1 | |
| SCHEMBL19121774 | 0.77 | ALDH1A1 (0.56) | ALDH1A1NPY2RKDM4EKMT2AMEN1 | |
| SCHEMBL22773254 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPY2RKDM4EKMT2AMEN1 | |
| SCHEMBL21382028 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPY2RKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231551-A1 | COMPOSITIONS AND USES THEREOF | UNIVERSITY OF VIRGINIA | 2020-07-23 | — | — | US | disclosed |
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231551-A1 | COMPOSITIONS AND USES THEREOF | CYP11B2, NQO1, CYP11B1 | PKM 1374/4885ALDH1A1 274/4885POLB 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.