Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460610 | 0.95 | NPY2R (0.49) | ALDH1A1PKMPOLBNPY2RKMT2A | |
| SCHEMBL7430849 | 0.92 | PKM (0.60) | ALDH1A1PKMPOLBNPY2RKMT2A | |
| SCHEMBL10461596 | 0.84 | MEN1 (0.56) | ALDH1A1PKMPOLBNPY2RHTR2A | |
| SCHEMBL10460811 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PKMPOLBNPY2RKMT2A | |
| SCHEMBL10460341 | 0.82 | NPY2R (0.55) | ALDH1A1PKMNPY2RKMT2AMEN1 | |
| SCHEMBL7432420 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PKMPOLBKMT2AMEN1 | |
| SCHEMBL5915273 | 0.77 | NPY2R (0.60) | ALDH1A1PKMNPY2RKMT2AMEN1 | |
| SCHEMBL19121774 | 0.71 | ALDH1A1 (0.56) | ALDH1A1NPY2RKMT2AMEN1KDM4E | |
| SCHEMBL22773254 | 0.71 | ALDH1A1 (0.63) | ALDH1A1NPY2RKMT2AMEN1KDM4E | |
| SCHEMBL21382028 | 0.71 | ALDH1A1 (0.63) | ALDH1A1NPY2RKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |