Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151262 | 0.81 | GAA (0.34) | PPIDOPRM1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5836128 | 0.79 | GHSR (0.48) | GHSRPTPRCAVPR2CXCR5 | |
| SCHEMBL7433540 | 0.79 | MEN1 (0.33) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7437988 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL260291 | 0.78 | BRD4 (0.43) | BRD4GHSROPRM1SLC22A1SLC6A4 | |
| SCHEMBL7432520 | 0.78 | ALDH1A1 (0.32) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12992703 | 0.77 | BRD4 (0.49) | BRD4OPRM1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL3633908 | 0.76 | BRD4 (0.46) | BRD4GHSROPRM1SLC22A1SLC6A4 | |
| SCHEMBL5835047 | 0.73 | GHSR (0.46) | GHSRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7411019 | 0.72 | CTSL (0.46) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |