Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27175299 | 0.91 | CTSL (0.46) | CTSLCTSBCTSSSYKCTSK | |
| SCHEMBL7360632 | 0.84 | CTSL (0.49) | CTSLCTSBCTSSDDB1CRBN | |
| SCHEMBL7528358 | 0.83 | CTSL (0.56) | CTSLCTSBCTSSSYKDDB1 | |
| SCHEMBL550418 | 0.83 | CTSL (0.56) | CTSLCTSBCTSSSYKDDB1 | |
| SCHEMBL8296463 | 0.82 | CTSL (0.47) | CTSLCTSBCTSSDDB1CRBN | |
| SCHEMBL4823158 | 0.82 | CTSS (0.54) | CTSLCTSBCTSSSYKDDB1 | |
| SCHEMBL7432520 | 0.80 | ALDH1A1 (0.32) | CTSKMAPT | |
| SCHEMBL1143391 | 0.80 | CTSL (0.51) | CTSLCTSBCTSSSYKDDB1 | |
| SCHEMBL5592243 | 0.79 | CTSB (0.45) | CTSLCTSBCTSSDDB1CRBN | |
| SCHEMBL12661032 | 0.79 | CTSL (0.54) | CTSLCTSBCTSSDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854275-A | Cyclic imide derivatives | PFIZER INC. (US) | 1998-12-29 | — | — | US | disclosed |